Led by Horatio Caine (David Caruso), the Miami-Dade Crime Scene Investigators work amid the steamy, tropical surroundings and cultural crossroads of Miami. Caine, a former bomb squad detective, often finds his reliance on gut instincts in conflict with DNA specialist Megan Donner (Kim Delaney), the former head of the unit. Together the investigators of CSI: Miami, collect and analyse the evidence to defend the memory of those who often cannot speak for themselves - the victims.